Journal of Advanced Research in Nanoscience and Nanotechnology

A Comprehensive Review of Nanodevice Manufacturing Advances for Biomedical Applications

2024-03-01T05:07:48+00:00

Nanotechnology has emerged as a revolutionary field with immense potential for transforming various industries, especially in the realm of biomedical applications. This review provides a comprehensive overview of the recent advances in the manufacture of nanodevices tailored for biomedical purposes. The focus is primarily on the synthesis methods, functionalization techniques, and diverse applications of these nanodevices, highlighting their impact on diagnostics, imaging, drug delivery, and therapeutic interventions.
In this comprehensive exploration, we delve into the intricacies of nanodevice synthesis, encompassing top-down and bottom-up approaches such as chemical vapor deposition, self-assembly, and template-assisted methods.
Moreover, we scrutinize the multifaceted applications of nanodevices in diagnostics, elucidating their pivotal role in biosensors, imaging agents, and point-of-care devices. The review further navigates through the revolutionary impact of nanotechnology on drug delivery systems, unraveling how nanodevices facilitate controlled and targeted release of therapeutic agents, thereby enhancing efficacy and minimizing side effects.
Beyond diagnostics and drug delivery, we explore the burgeoning field of therapeutic interventions facilitated by nanodevices. From hyperthermia and photodynamic therapy to gene therapy, these interventions showcase the versatility of nanotechnology in reshaping traditional approaches to treatment.
As the review unfolds, it not only encapsulates the remarkable strides made in the field but also confronts the challenges hindering the seamless integration of nanodevices into mainstream biomedical practices. We critically examine issues such as nanotoxicology, scalability, and the imperative need for rigorous clinical translation, paving the way for a comprehensive understanding of the current landscape.

Advancements in Nanomanufacturing: Pioneering the Future of Precision Engineering

2024-03-01T05:19:45+00:00

Nanomanufacturing, an avant-garde discipline at the intersection of science and engineering, involves the precise manipulation of materials at the nanoscale to construct functional structures and devices. This expansive review provides an in-depth exploration of recent breakthroughs in nanomanufacturing techniques, their myriad applications, and the potential paradigm-shifting impact on industries ranging from electronics to medicine, energy, and materials science.
Navigating the intricate landscape of nanomanufacturing methodologies, this review elucidates the evolution of top-down approaches, such as lithography, transcending traditional boundaries with advancements like extreme ultraviolet lithography (EUVL) and nanoimprint lithography. Simultaneously, it delves into the transformative potential of bottom-up techniques, including self-assembly and additive manufacturing, showcasing how these processes harness natural forces to achieve unparalleled precision in the creation of nanoscale structures.
The practical implications of nanomanufacturing are scrutinized across diverse sectors. In the realm of nanoelectronics, the review dissects the transformative impact on transistor fabrication, quantum dot-based memory devices, and the seamless integration of 2D materials, paving the way for the next era of computing technologies. In medicine, nanomanufacturing is unraveling novel avenues for drug delivery, diagnostics, and personalized medicine, with nanoparticle-based systems and nanoscale sensors poised to redefine healthcare standards.

Different Nanoparticles of Tinospora Cordifolia (Giloy), and its Application

2024-03-01T05:47:09+00:00

The utilisation of Tinospora cordifolia, commonly known as “Giloy,” extends beyond traditional medicinal practices, with a focus on exploring its potential in nanoparticle synthesis and applications. This botanical marvel, rich in bioactive compounds, has been extensively studied for its diverse pharmacological effects, including immunomodulation, anti-inflammatory, and analgesic properties. However, its role in regulating lead toxicity has not been previously explored.
This article presents a comprehensive investigation into the synthesis of different nanoparticles of Tinospora cordifolia, including silver, copper, iron, zinc, and gold nanoparticles. The synthesis methods involve the plant extract and metal precursors, resulting in varied nanoparticle characteristics. The potential applications of these nanoparticles are explored, highlighting their catalytic degradation capabilities, antimicrobial, antifungal, and analgesic properties.
Specifically, the greenly synthesised copper nanoparticles exhibit notable catalytic degradation activity against hazardous dyes. Copper oxide nanoparticles display antimicrobial and antifungal activities, with promising effects against gram-negative and gram-positive bacteria, as well as pathogenic fungi. Silver nanoparticles exhibit remarkable antibacterial and antifungal activities against multidrug-resistant strains and demonstrate inhibitory effects against Clamydomonas reinhardtii.
Moreover, the article delves into the potential of these nanoparticles for addressing lead toxicity. The study focuses on investigating how the aqueous extract from the stem and leaves of Tinospora cordifolia affects lead-induced haematological alterations, providing a novel perspective on the plant’s therapeutic applications.

Environmental Implications of Nanotechnology

2024-03-01T05:58:05+00:00

Nanotechnology, hailed for its transformative potential across diverse industries, has ignited a wave of innovation and progress. However, this surge in nanomaterial development and applications has stirred apprehensions regarding its environmental repercussions. This comprehensive review navigates the intricate terrain of the environmental aspects of nanotechnology, offering a nuanced exploration of the life cycle of nanomaterials, their interactions with ecosystems, and emerging strategies for fostering sustainable and responsible nanotechnology development.
In the unfolding panorama of nanomaterial life cycles, a critical examination is undertaken, unraveling the complexities from synthesis to disposal. Special attention is given to the environmental hotspots during manufacturing, as well as the potential release of nanomaterials into air, water, and soil. The elucidation of these life cycles is underscored by the integration of life cycle assessment (LCA) methodologies, providing a comprehensive framework for evaluating and mitigating environmental footprints.
Navigating the regulatory landscape, the review assesses the adequacy of existing frameworks for governing nanomaterials. The discourse extends to international collaborations, emphasizing the need for harmonized approaches to ensure a global commitment to environmental protection. In tandem, sustainable nanotechnology emerges as a beacon of hope, with green synthesis methods, eco-friendly design principles, and the use of benign materials heralding a new era of environmentally conscious innovation.
As we peer into the future, persistent challenges beckon exploration. The conclusion resonates with a call for standardized testing protocols, advances in nanomaterial characterization techniques, and a deeper understanding of their interactions within complex ecosystems. The narrative unfolds as a holistic exploration, advocating for a balanced synthesis of innovation and environmental stewardship in the ever-evolving realm of nanotechnology.

Nanobiology: Bridging the Micro and Macro Worlds for Revolutionary Advances in Life Sciences

2024-03-01T06:05:57+00:00

Nanobiology, an interdisciplinary convergence of nanotechnology and biology, represents a paradigm shift in our understanding and manipulation of living systems at the nanoscale. This review delves into the dynamic landscape of nanobiology, exploring recent breakthroughs and their implications across diagnostics, therapeutics, imaging, and fundamental biological insights.
At the forefront of diagnostic innovation, nanobiology leverages nanoscale biosensors, nanoparticles, and cutting-edge nanodevices to revolutionize disease detection. Quantum dots, with their exceptional optical properties, stand out as versatile tools for real-time imaging and biomolecule detection, exemplifying the potential for early and precise diagnostics.
Therapeutically, nanobiology has redefined drug delivery strategies, employing nanoparticles and nanocarriers for targeted and controlled release of therapeutic agents. This precision approach minimizes side effects, enhances treatment efficacy, and offers promising avenues for gene therapy, unlocking new possibilities for addressing genetic disorders at their roots.
In the realm of imaging, nanobiology transcends the limitations of traditional microscopy. Super-resolution techniques such as STED and PALM push the boundaries of resolution, unraveling intricate cellular structures and molecular processes. Beyond diagnostics and therapeutics, nanobiology’s impact on neuroscience is profound, enabling the monitoring of neural activity, targeted drug delivery to the brain, and the exploration of novel therapies for neurological disorders.

Progress in the Production of Nanodevices for Biomedical Uses: An Extensive Analysis

2024-03-01T06:17:52+00:00

Nanotechnology has emerged as a transformative force in biomedical research, offering innovative solutions to long-standing challenges in diagnostics, drug delivery, and therapeutic interventions. This comprehensive review explores the dynamic landscape of nanodevice manufacturing for biomedical applications, encompassing the latest breakthroughs, persistent challenges, and the promising trajectory of this rapidly evolving field. In recent years, the synthesis of nanomaterials has gained significant attention due to their unique physicochemical properties. Carbon-based materials, metallic nanoparticles, liposomes, and polymer-based nanocarriers constitute the arsenal of materials under examination, each with distinct advantages tailored to specific biomedical applications.
The manufacturing of nanodevices involves an array of sophisticated fabrication techniques, ranging from traditional lithography to cutting-edge 3D printing. This section critically evaluates these methods, exploring their scalability, precision, and adaptability to diverse biomedical contexts. Biomedical imaging and diagnostics have experienced a paradigm shift with the integration of nanodevices. We scrutinize the utilization of nanoscale contrast agents, quantum dots, and multifunctional nanop
articles, elucidating their roles in enhancing imaging modalities for early disease detection and accurate monitoring. Furthermore, the review navigates through drug delivery systems, spotlighting nanocarriers’ pivotal role in improving drug solubility, bioavailability, and targeted delivery, thereby revolutionizing therapeutic efficacy.
While the therapeutic potential of nanodevices in cancer therapy, gene therapy, and regenerative medicine is profound, challenges persist. Regulatory hurdles, concerns regarding nanotoxicity, and the imperative for standardization necessitate focused attention. Looking ahead, the integration of artificial intelligence, the development of multifunctional nanodevices, and collaborative interdisciplinary efforts hold the promise of propelling nanotechnology into mainstream personalized and precision medicine.